Annotations for the selected gene list

Probe Symbol Description Function Chromosome Chromosome Location GenBank LocusLink Cytoband UniGene PubMed Gene Ontology Pathway
200953_s_at CCND2 cyclin D2   12 4253198 NM_001759 12p13 Hs.376071 50

regulation of progression through cell cycle

protein binding

nucleus

cell cycle

cell division

Cell cycle

Wnt signaling pathway

Focal adhesion

Jak-STAT signaling pathway

Colorectal cancer

205858_at NGFR nerve growth factor receptor (TNFR superfamily, member 16)   17 44927665 NM_002507 17q21-q22 Hs.415768 68

transmembrane receptor activity

protein binding

plasma membrane

integral to plasma membrane

apoptosis

signal transduction

nervous system development

cell differentiation

Neurodegenerative Disorders

Cytokine-cytokine receptor interaction

202664_at WASPIP Wiskott-Aldrich syndrome protein interacting protein   2 -175132548 AW058622 2q31.1 Hs.591641 19

actin binding

profilin binding

protein complex assembly

actin polymerization and/or depolymerization

actin cytoskeleton

 
219263_at RNF128 ring finger protein 128   X 105823723, 105856549 NM_024539 Xq22.3 Hs.496542 6

protein binding

proteolysis

ubiquitin cycle

peptidase activity

zinc ion binding

metal ion binding

 
219764_at FZD10 frizzled homolog 10 (Drosophila)   12 129212984 NM_007197 12q24.33 Hs.31664 5

receptor activity

non-G-protein coupled 7TM receptor activity

G-protein coupled receptor activity

integral to plasma membrane

G-protein coupled receptor protein signaling pathway

frizzled signaling pathway

development

membrane

Wnt receptor activity

Wnt signaling pathway

214456_x_at SAA2 serum amyloid A2   11 -18223364 M23699 11p15.1-p14 Hs.1955 Hs.632144 36    
218273_s_at PPM2C protein phosphatase 2C, magnesium-dependent, catalytic subunit   8 94998337 NM_018444 8q22.1 Hs.22265 17    
40284_at FOXA2 forkhead box A2   20 -22509822 AB028021 20p11 Hs.155651 22

transcription factor activity

nucleus

transcription

regulation of transcription, DNA-dependent

sequence-specific DNA binding

Maturity onset diabetes of the young

203413_at NELL2 NEL-like 2 (chicken)   12 -43188331 NM_006159 12q13.11-q13.12 Hs.505326 10

structural molecule activity

calcium ion binding

protein binding

extracellular region

cell adhesion

 
213425_at WNT5A wingless-type MMTV integration site family, member 5A   3 -55474783 AI968085 3p21-p14 Hs.152213 23

receptor binding

extracellular region

extracellular space

soluble fraction

signal transduction

frizzled-2 signaling pathway

cell-cell signaling

morphogenesis

Wnt signaling pathway

Hedgehog signaling pathway

202499_s_at SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3   12 -7963093 NM_006931 12p13.3 Hs.419240 17

transporter activity

sugar porter activity

glucose transporter activity

glucose transporter activity

membrane fraction

carbohydrate metabolism

carbohydrate transport

glucose transport

membrane

integral to membrane

 
220217_x_at SPANXC SPANX family, member C   X -140163262 NM_022661 Xq27.1 Hs.558533 5

biological process unknown

molecular function unknown

nucleus

 
216623_x_at TNRC9 trinucleotide repeat containing 9   16   AK025084 16q12.1 Hs.460789 2

chromatin

DNA binding

nucleus

regulation of transcription, DNA-dependent

 
202669_s_at EFNB2 ephrin-B2   13 -105940098 U16797 13q33 Hs.149239 50

plasma membrane

integral to plasma membrane

cell-cell signaling

nervous system development

morphogenesis

membrane

cell differentiation

ephrin receptor binding

Axon guidance

205399_at DCAMKL1 doublecortin and CaM kinase-like 1   13 -35243477 NM_004734 13q13 Hs.507755 10

nucleotide binding

protein serine/threonine kinase activity

receptor signaling protein activity

protein binding

ATP binding

integral to plasma membrane

protein amino acid phosphorylation

intracellular signaling cascade

central nervous system development

endosome transport

kinase activity

transferase activity

cell differentiation

 
205625_s_at CALB1 calbindin 1, 28kDa   8 -91140013 AW014927 8q21.3-q22.1 Hs.65425 21

vitamin D binding

calcium ion binding

protein binding

 
200982_s_at ANXA6 annexin A6   5 -150460460 NM_001155 5q32-q34 Hs.412117 27

calcium ion binding

protein binding

calcium-dependent phospholipid binding

 
200701_at NPC2 Niemann-Pick disease, type C2   14 -74016396 NM_006432 14q24.3 Hs.433222 20

regulation of isoprenoid metabolism

enzyme binding

cholesterol homeostasis

 
220922_s_at SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1   X 140505524, -140499471 NM_013453 Xq27.1 Hs.334464 6

nucleus

cytoplasm

spermatogenesis

 
221214_s_at NELF nasal embryonic LHRH factor   9 -139462497 NM_015537 9q34.3 Hs.455336 10    
202628_s_at SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1   7 100557171 NM_000602 7q21.3-q22 Hs.414795 236

protease binding

serine-type endopeptidase inhibitor activity

extracellular region

blood coagulation

plasminogen activator activity

fibrinolysis

Complement and coagulation cascades

205932_s_at MSX1 msh homeobox homolog 1 (Drosophila)   4 4912299 NM_002448 4p16.3-p16.1 Hs.424414 Hs.621772 35

skeletal development

transcription factor activity

nucleus

regulation of transcription, DNA-dependent

development

organ morphogenesis

sequence-specific DNA binding

 
211458_s_at GABARAPL3 GABA(A) receptors associated protein like 3   15   AF180519 15q26.1 Hs.592014 1

microtubule

 
211343_s_at COL13A1 collagen, type XIII, alpha 1   10 71231649 M33653 10q22 Hs.211933 17

collagen type XIII

cytoplasm

plasma membrane

phosphate transport

 
213711_at KRT81 keratin 81   12 -50965965 NM_002281 12q13 Hs.584773 16

structural molecule activity

intermediate filament

Cell Communication

211429_s_at SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1   14 -93914450 AF119873 14q32.1 Hs.525557 119

serine-type endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

protein binding

extracellular region

extracellular space

acute-phase response

Complement and coagulation cascades

202912_at ADM adrenomedullin   11 10283217 NM_001124 11p15.4 Hs.441047 122

hormone activity

extracellular region

extracellular space

soluble fraction

cAMP biosynthesis

progesterone biosynthesis

signal transduction

cell-cell signaling

pregnancy

excretion

circulation

response to wounding

 
201860_s_at PLAT plasminogen activator, tissue   8 -42151911 NM_000930 8p12 Hs.491582 116

serine-type endopeptidase activity

extracellular region

protein modification

proteolysis

proteolysis

blood coagulation

peptidase activity

plasminogen activator activity

Complement and coagulation cascades

204268_at S100A2 S100 calcium binding protein A2   1 -151800210 NM_005978 1q21 Hs.516484 31

calcium ion binding

cellular component unknown

endothelial cell migration

 
214774_x_at TNRC9 trinucleotide repeat containing 9   16   AK027006 16q12.1 Hs.460789 2

chromatin

DNA binding

nucleus

regulation of transcription, DNA-dependent

 
201125_s_at ITGB5 integrin, beta 5   3 -125964485 NM_002213 3q21.2 Hs.536663 42

receptor activity

protein binding

cell adhesion

cell-matrix adhesion

integrin-mediated signaling pathway

development

integrin complex

membrane

integral to membrane

Focal adhesion

ECM-receptor interaction

Regulation of actin cytoskeleton

204881_s_at UGCG UDP-glucose ceramide glucosyltransferase   9 113699026 NM_003358 9q31 Hs.304249 Hs.593014 17

extracellular space

membrane fraction

cytoplasm

endoplasmic reticulum

glucosylceramide biosynthesis

glycosphingolipid biosynthesis

ceramide glucosyltransferase activity

epidermis development

membrane

integral to membrane

transferase activity, transferring glycosyl groups

Sphingolipid metabolism

Glycan structures - biosynthesis 2

204532_x_at UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9   2 234245282 NM_021027 2q37 Hs.124112 25

endoplasmic reticulum

microsome

microsome

xenobiotic metabolism

metabolism

metabolism

glucuronosyltransferase activity

membrane

integral to membrane

Pentose and glucuronate interconversions

Androgen and estrogen metabolism

Starch and sucrose metabolism

Porphyrin and chlorophyll metabolism

Metabolism of xenobiotics by cytochrome P450

209129_at TRIP6 thyroid hormone receptor interactor 6   7 100302885 AF000974 7q22 Hs.534360 20

interleukin-1 receptor binding

protein binding

protein binding

focal adhesion

zinc ion binding

release of cytoplasmic sequestered NF-kappaB

kinase binding

positive regulation of cell migration

interleukin-1 receptor complex

metal ion binding

thyroid hormone receptor binding

focal adhesion formation

 
210869_s_at MCAM melanoma cell adhesion molecule   11 -118684444 M29277 11q23.3 Hs.599039 27

protein binding

plasma membrane

integral to plasma membrane

cell adhesion

morphogenesis

 
202627_s_at SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1   7 100557171 AL574210 7q21.3-q22 Hs.414795 236

protease binding

serine-type endopeptidase inhibitor activity

extracellular region

blood coagulation

plasminogen activator activity

fibrinolysis

Complement and coagulation cascades

209160_at AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)   10 5126567 AB018580 10p15-p14 Hs.78183 31

aldo-keto reductase activity

estradiol 17-beta-dehydrogenase activity

electron transport

prostaglandin metabolism

oxidoreductase activity

prostaglandin-F synthase activity

3-alpha-hydroxysteroid dehydrogenase (A-specific) activity

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

Arachidonic acid metabolism

Metabolism of xenobiotics by cytochrome P450

202207_at ARL4C ADP-ribosylation factor-like 4C   2 -235066426 BG435404 2q37.1 Hs.111554 7

nucleotide binding

GTPase activity

GTP binding

intracellular

nucleus

rRNA processing

small GTPase mediated signal transduction

 
201311_s_at SH3BGRL SH3 domain binding glutamic acid-rich protein like   X 80344277 AL515318 Xq13.3 Hs.108029 7

SH3/SH2 adaptor activity

nucleus

cytoplasm

 
209772_s_at CD24 CD24 molecule   6 -19611913 X69397 6q21 Hs.375108 26

plasma membrane

humoral immune response

GPI anchor binding

Hematopoietic cell lineage

212063_at CD44 CD44 molecule (Indian blood group)   11 35116992 BE903880 11p13 Hs.502328 192

receptor activity

collagen binding

hyaluronic acid binding

hyaluronic acid binding

integral to plasma membrane

cell adhesion

cell-matrix adhesion

membrane

cell-cell adhesion

ECM-receptor interaction

Hematopoietic cell lineage

217841_s_at PPME1 protein phosphatase methylesterase 1   11 73560015 NM_016147 11q13.4 Hs.503251 3

serine esterase activity

protein phosphatase inhibitor activity

protein binding

protein amino acid demethylation

aromatic compound metabolism

protein phosphatase type 2A regulator activity

hydrolase activity

carboxylic ester hydrolase activity

protein phosphatase 2A binding

protein C-terminal methylesterase activity

2,4-Dichlorobenzoate degradation

Butanoate metabolism

Alkaloid biosynthesis II

202443_x_at NOTCH2 Notch homolog 2 (Drosophila)   1 -120255700 AA291203 1p13-p11 Hs.487360 Hs.515947 39

cell fate determination

ligand-regulated transcription factor activity

receptor activity

receptor activity

calcium ion binding

protein binding

nucleus

integral to plasma membrane

transcription

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

anti-apoptosis

induction of apoptosis

cell cycle arrest

Notch signaling pathway

Notch signaling pathway

nervous system development

negative regulation of cell proliferation

organ morphogenesis

cell surface

membrane

integral to membrane

cell growth

stem cell maintenance

hemopoiesis

cell differentiation

positive regulation of Ras protein signal transduction

protein heterodimerization activity

regulation of development

Dorso-ventral axis formation

Notch signaling pathway

218718_at PDGFC platelet derived growth factor C   4 -157902213 NM_016205 4q32 Hs.570855 20  

Cytokine-cytokine receptor interaction

Focal adhesion

Gap junction

200920_s_at BTG1 B-cell translocation gene 1, anti-proliferative   12 -91061033 AL535380 12q22 Hs.255935 Hs.585087 18

transcription cofactor activity

nucleus

nucleus

cytoplasm

spermatid development

negative regulation of cell proliferation

cell migration

kinase binding

negative regulation of cell growth

regulation of apoptosis

positive regulation of enzyme activity

regulation of transcription

positive regulation of endothelial cell differentiation

positive regulation of myoblast differentiation

positive regulation of angiogenesis

 
212531_at LCN2 lipocalin 2 (oncogene 24p3)   9 129951552 NM_005564 9q34 Hs.204238 32

transporter activity

binding

soluble fraction

cytoplasm

transport

 
200632_s_at NDRG1 N-myc downstream regulated gene 1   8 -134318595 NM_006096 8q24.3 Hs.372914 39

nucleus

response to metal ion

cell differentiation

 
210764_s_at CYR61 cysteine-rich, angiogenic inducer, 61   1 85819047 AF003114 1p31-p22 Hs.8867 47

regulation of cell growth

insulin-like growth factor binding

extracellular region

chemotaxis

cell adhesion

heparin binding

cell proliferation

morphogenesis

 
205990_s_at WNT5A wingless-type MMTV integration site family, member 5A   3 -55474783 NM_003392 3p21-p14 Hs.152213 23

receptor binding

extracellular region

extracellular space

soluble fraction

signal transduction

frizzled-2 signaling pathway

cell-cell signaling

morphogenesis

Wnt signaling pathway

Hedgehog signaling pathway

211564_s_at PDLIM4 PDZ and LIM domain 4   5 131621285 BC003096 5q31.1 Hs.424312 13

protein binding

zinc ion binding

metal ion binding

 
204351_at S100P S100 calcium binding protein P   4 6746466 NM_005980 4p16 Hs.2962 26

magnesium ion binding

calcium ion binding

nucleus

cytoplasm

endothelial cell migration

calcium-dependent protein binding

 
201445_at CNN3 calponin 3, acidic   1 -95135095 NM_001839 1p22-p21 Hs.483454 10

actin binding

actin binding

calmodulin binding

tropomyosin binding

smooth muscle contraction

cellular component unknown

troponin C binding

actomyosin structure organization and biogenesis

 
204891_s_at LCK lymphocyte-specific protein tyrosine kinase   1 32512298, 32489426 NM_005356 1p34.3 Hs.470627 232

regulation of progression through cell cycle

regulation of progression through cell cycle

nucleotide binding

pericentriolar material

pericentriolar material

glycoprotein binding

protein-tyrosine kinase activity

protein-tyrosine kinase activity

protein-tyrosine kinase activity

protein serine/threonine phosphatase activity

protein serine/threonine phosphatase activity

ATP binding

plasma membrane

plasma membrane

protein amino acid phosphorylation

protein amino acid phosphorylation

protein amino acid phosphorylation

zinc ion homeostasis

zinc ion homeostasis

induction of apoptosis

induction of apoptosis

caspase activation

caspase activation

intracellular signaling cascade

intracellular signaling cascade

intracellular signaling cascade

Ras protein signal transduction

Ras protein signal transduction

protein C-terminus binding

transferase activity

protein kinase binding

hemopoiesis

hemopoiesis

T cell differentiation

T cell differentiation

SH2 domain binding

SH2 domain binding

response to drug

response to drug

CD4 receptor binding

CD8 receptor binding

phosphoinositide 3-kinase binding

lipid raft

lipid raft

positive regulation of T cell receptor signaling pathway

positive regulation of T cell receptor signaling pathway

positive regulation of T cell activation

positive regulation of T cell activation

ATPase binding

release of sequestered calcium ion into cytosol

regulation of lymphocyte activation

regulation of lymphocyte activation

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

201983_s_at EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)   7 55054218 AW157070 7p12 Hs.488293 599

nucleotide binding

ossification

double-stranded DNA binding

MAP/ERK kinase kinase activity

transmembrane receptor activity

epidermal growth factor receptor activity

epidermal growth factor receptor activity

protein binding

ATP binding

extracellular space

nucleus

cytoplasm

endosome

plasma membrane

protein amino acid phosphorylation

response to stress

cell cycle

cell surface receptor linked signal transduction

epidermal growth factor receptor signaling pathway

phospholipase C activation

cell proliferation

integral to membrane

cell-cell adhesion

transferase activity

AP-2 adaptor complex

nitric-oxide synthase regulator activity

positive regulation of cell migration

positive regulation of phosphorylation

calcium-dependent phospholipase A2 activation

positive regulation of MAPK activity

positive regulation of nitric oxide biosynthesis

negative regulation of progression through cell cycle

protein heterodimerization activity

positive regulation of epithelial cell proliferation

regulation of peptidyl-tyrosine phosphorylation

regulation of nitric-oxide synthase activity

actin filament binding

protein insertion into membrane

MAPK signaling pathway

Calcium signaling pathway

Cytokine-cytokine receptor interaction

Dorso-ventral axis formation

Focal adhesion

Adherens junction

Gap junction

Regulation of actin cytoskeleton

GnRH signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Colorectal cancer

218087_s_at SORBS1 sorbin and SH3 domain containing 1   10 -97061519 NM_015385 10q23.3-q24.1 Hs.38621 26

stress fiber

actin binding

insulin receptor binding

nucleus

zonula adherens

cell-substrate adherens junction

transport

insulin receptor signaling pathway

glucose transport

membrane

stress fiber formation

lipid raft

focal adhesion formation

PPAR signaling pathway

Adherens junction

Insulin signaling pathway

48106_at FLJ20489     12 46453257 H14241 12q13.11 Hs.438867 1    
219836_at ZBED2 zinc finger, BED-type containing 2   3 -112794437 NM_024508 3q13.13 Hs.136912 2

DNA binding

zinc ion binding

metal ion binding

 
202668_at EFNB2 ephrin-B2   13 -105940098 BF001670 13q33 Hs.149239 50

plasma membrane

integral to plasma membrane

cell-cell signaling

nervous system development

morphogenesis

membrane

cell differentiation

ephrin receptor binding

Axon guidance

204798_at MYB v-myb myeloblastosis viral oncogene homolog (avian)   6 135544145 NM_005375 6q22-q23 Hs.531941 49

nuclear mRNA splicing, via spliceosome

DNA binding

protein binding

nucleus

spliceosome complex

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

cell cycle

nuclear matrix

transcriptional activator activity

transcription regulator activity

regulation of transcription

 
201163_s_at IGFBP7 insulin-like growth factor binding protein 7   4 -57592002 NM_001553 4q12 Hs.479808 27

regulation of cell growth

insulin-like growth factor binding

extracellular region

negative regulation of cell proliferation

 
204115_at GNG11 guanine nucleotide binding protein (G protein), gamma 11   7 93388951 NM_004126 7q21 Hs.83381 13

signal transducer activity

heterotrimeric G-protein complex

signal transduction

G-protein coupled receptor protein signaling pathway

membrane

 
212226_s_at PPAP2B phosphatidic acid phosphatase type 2B   1 -56733022 AA628586 1pter-p22.1 Hs.405156 Hs.638793 11

phosphoprotein phosphatase activity

lipid metabolism

phosphatidate phosphatase activity

germ cell migration

membrane

integral to membrane

hydrolase activity

Glycerolipid metabolism

Glycerophospholipid metabolism

Sphingolipid metabolism

219288_at C3orf14 chromosome 3 open reading frame 14   3 62280435 NM_020685 3p14.2 Hs.47166 1    
206218_at MAGEB2 melanoma antigen family B, 2   X 30143600 NM_002364 Xp21.3 Hs.113824 8    
200878_at EPAS1 endothelial PAS domain protein 1   2 46378066 AF052094 2p21-p16 Hs.468410 46

angiogenesis

response to hypoxia

RNA polymerase II transcription factor activity, enhancer binding

transcription coactivator activity

signal transducer activity

protein binding

nucleus

regulation of transcription, DNA-dependent

transcription from RNA polymerase II promoter

signal transduction

cell differentiation

histone acetyltransferase binding

 
218280_x_at HIST2H2AA3 histone 2, H2aa3   1 -148080409, 148089251 NM_003516 1q21.2 Hs.530461 18

nucleosome

DNA binding

nucleus

chromosome

nucleosome assembly

chromosome organization and biogenesis (sensu Eukaryota)

 
202286_s_at TACSTD2 tumor-associated calcium signal transducer 2   1 -58813230 J04152 1p32-p31 Hs.23582 22

receptor activity

cytosol

integral to plasma membrane

cell surface receptor linked signal transduction

visual perception

cell proliferation

membrane

response to stimulus

 
204083_s_at TPM2 tropomyosin 2 (beta)   9 -35672923, -35671989 NM_003289 9p13.2-p13.1 Hs.300772 24

actin binding

cytoskeleton

muscle thin filament tropomyosin

structural constituent of muscle

 
209087_x_at MCAM melanoma cell adhesion molecule   11 -118684444 AF089868 11q23.3 Hs.599039 27

protein binding

plasma membrane

integral to plasma membrane

cell adhesion

morphogenesis

 
204589_at NUAK1 NUAK family, SNF1-like kinase, 1   12 -104981254 NM_014840 12q23.3 Hs.524692 12

nucleotide binding

magnesium ion binding

protein serine/threonine kinase activity

ATP binding

protein amino acid phosphorylation

transferase activity

 
203423_at RBP1 retinol binding protein 1, cellular   3 -140718973 NM_002899 3q23 Hs.529571 28

vitamin A metabolism

transport

lipid binding

retinal binding

retinol binding

 
202497_x_at SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14   12 -7857664 AI631159 12p13.31 Hs.419240 2

transporter activity

sugar porter activity

glucose transporter activity

spermatogenesis

carbohydrate transport

membrane

integral to membrane

cell differentiation

 
205352_at SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1   3 168936216 NM_005025 3q26.1 Hs.478153 17

serine-type endopeptidase inhibitor activity

central nervous system development

peripheral nervous system development

 
201162_at IGFBP7 insulin-like growth factor binding protein 7   4 -57592002 NM_001553 4q12 Hs.479808 27

regulation of cell growth

insulin-like growth factor binding

extracellular region

negative regulation of cell proliferation

 
213479_at NPTX2 neuronal pentraxin II   7 98084544 U26662 7q21.3-q22.1 Hs.3281 9

calcium ion binding

sugar binding

molecular function unknown

synaptic transmission

cellular component unknown

 
208791_at CLU clusterin   8 -27510368 M25915 8p21-p12 Hs.436657 84

extracellular space

lipid metabolism

apoptosis

complement activation, classical pathway

cell death

innate immune response

 
201820_at KRT5 keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types)   12 -51194627 NM_000424 12q12-q13 Hs.433845 57

structural molecule activity

structural constituent of cytoskeleton

protein binding

intermediate filament

intermediate filament

epidermis development

Cell Communication

210095_s_at IGFBP3 insulin-like growth factor binding protein 3   7 -45918374 M31159 7p13-p12 Hs.450230 170

regulation of cell growth

insulin-like growth factor binding

insulin-like growth factor binding

extracellular region

extracellular region

protein tyrosine phosphatase activator activity

negative regulation of signal transduction

positive regulation of apoptosis

positive regulation of myoblast differentiation

metal ion binding

 
208607_s_at SAA2 serum amyloid A2   11 -18223364 NM_030754 11p15.1-p14 Hs.1955 Hs.632144 36    
210467_x_at MAGEA12 melanoma antigen family A, 12   X -151649951 BC003408 Xq28 Hs.169246 6

biological process unknown

molecular function unknown

cellular component unknown

 
202552_s_at CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)   2 36436900 NM_016441 2p21 Hs.332847 6

regulation of cell growth

cysteine-type endopeptidase activity

serine-type endopeptidase inhibitor activity

insulin-like growth factor receptor activity

insulin-like growth factor binding

extracellular region

membrane fraction

proteolysis

nervous system development

membrane

integral to membrane

 
221765_at UGCG UDP-glucose ceramide glucosyltransferase   9 113699026 AI378044 9q31 Hs.304249 Hs.593014 17

extracellular space

membrane fraction

cytoplasm

endoplasmic reticulum

glucosylceramide biosynthesis

glycosphingolipid biosynthesis

ceramide glucosyltransferase activity

epidermis development

membrane

integral to membrane

transferase activity, transferring glycosyl groups

Sphingolipid metabolism

Glycan structures - biosynthesis 2

202267_at LAMC2 laminin, gamma 2   1 181422021 NM_005562 1q25-q31 Hs.591484 45

protein binding

basement membrane

laminin-5

cell adhesion

heparin binding

epidermis development

Cell Communication

Focal adhesion

ECM-receptor interaction

204341_at TRIM16 tripartite motif-containing 16   17 -15472005 NM_006470 17p11.2 Hs.123534 6

transcription factor activity

intracellular

cytoplasm

zinc ion binding

metal ion binding

 
210220_at FZD2 frizzled homolog 2 (Drosophila)   17 39990450 L37882 17q21.1 Hs.142912 10

receptor activity

non-G-protein coupled 7TM receptor activity

G-protein coupled receptor activity

integral to plasma membrane

establishment of tissue polarity

G-protein coupled receptor protein signaling pathway

development

membrane

Wnt receptor signaling pathway

Wnt signaling pathway

Colorectal cancer

203720_s_at ERCC1 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)   19 -50604711, -50608532 NM_001983 19q13.2-q13.3 Hs.435981 39

nucleotide-excision repair complex

damaged DNA binding

endonuclease activity

intracellular

nucleus

DNA repair

nucleotide-excision repair

hydrolase activity

sequence-specific DNA binding

 
202551_s_at CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)   2 36436900 BG546884 2p21 Hs.332847 6

regulation of cell growth

cysteine-type endopeptidase activity

serine-type endopeptidase inhibitor activity

insulin-like growth factor receptor activity

insulin-like growth factor binding

extracellular region

membrane fraction

proteolysis

nervous system development

membrane

integral to membrane

 
205632_s_at PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta   9 70547029, 70510435 NM_003558 9q13 Hs.534371 11

membrane

kinase activity

1-phosphatidylinositol-4-phosphate 5-kinase activity

transferase activity

Inositol phosphate metabolism

Phosphatidylinositol signaling system

Regulation of actin cytoskeleton

204153_s_at MFNG manic fringe homolog (Drosophila)   22 -36195048 NM_002405 22q12 Hs.517603 16

extracellular space

pattern specification

membrane

integral to membrane

transferase activity, transferring glycosyl groups

Notch signaling pathway

202733_at P4HA2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II   5 -131556204 NM_004199 5q31 Hs.519568 11

procollagen-proline 4-dioxygenase activity

iron ion binding

protein binding

endoplasmic reticulum

electron carrier activity

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

protein metabolism

L-ascorbic acid binding

metal ion binding

Arginine and proline metabolism

201272_at AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)   7 -133777646 NM_001628 7q35 Hs.521212 46

aldehyde reductase activity

extracellular space

carbohydrate metabolism

electron carrier activity

oxidoreductase activity

Pentose and glucuronate interconversions

Fructose and mannose metabolism

Galactose metabolism

Glycerolipid metabolism

Pyruvate metabolism

204688_at SGCE sarcoglycan, epsilon   7 -94052477 NM_003919 7q21-q22 Hs.371199 24

calcium ion binding

protein binding

cytoskeleton

integral to plasma membrane

cell-matrix adhesion

muscle development

sarcoglycan complex

membrane

 
211340_s_at MCAM melanoma cell adhesion molecule   11 -118684444 M28882 11q23.3 Hs.599039 27

protein binding

plasma membrane

integral to plasma membrane

cell adhesion

morphogenesis

 
49077_at PPME1 protein phosphatase methylesterase 1   11 73560015 AL040538 11q13.4 Hs.503251 3

serine esterase activity

protein phosphatase inhibitor activity

protein binding

protein amino acid demethylation

aromatic compound metabolism

protein phosphatase type 2A regulator activity

hydrolase activity

carboxylic ester hydrolase activity

protein phosphatase 2A binding

protein C-terminal methylesterase activity

2,4-Dichlorobenzoate degradation

Butanoate metabolism

Alkaloid biosynthesis II

208816_x_at ANXA2P2 annexin A2 pseudogene 2   9   M62898 9p13 Hs.534301 2    
214104_at GPR161 G protein-coupled receptor 161   1 -166326307, -166320622 AI703188 1q24.2 Hs.271809 Hs.632453 4

rhodopsin-like receptor activity

receptor activity

signal transduction

G-protein coupled receptor protein signaling pathway

membrane

integral to membrane

 
215043_s_at SMA5     5 -69812625 X83301 5q13 Hs.535014 1

biological process unknown

hydrolase activity, hydrolyzing O-glycosyl compounds

molecular function unknown

carbohydrate metabolism

cellular component unknown

 
218976_at DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12   10 -69226433, -69240973 NM_021800 10q22.1 Hs.260720 3

protein folding

heat shock protein binding

unfolded protein binding

 
202790_at CLDN7 claudin 7   17 -7104183 NM_001307 17p13 Hs.513915 20

structural molecule activity

tight junction

membrane

integral to membrane

calcium-independent cell-cell adhesion

identical protein binding

Cell adhesion molecules (CAMs)

Tight junction

Leukocyte transendothelial migration

215125_s_at UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9   2 234245282 AV691323 2q37 Hs.124112 25

endoplasmic reticulum

microsome

microsome

xenobiotic metabolism

metabolism

metabolism

glucuronosyltransferase activity

membrane

integral to membrane

Pentose and glucuronate interconversions

Androgen and estrogen metabolism

Starch and sucrose metabolism

Porphyrin and chlorophyll metabolism

Metabolism of xenobiotics by cytochrome P450

219014_at PLAC8 placenta-specific 8   4 -84230866 NM_016619 4q21.22 Hs.546392 7    
221773_at ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)   12 95112337 AW575374 12q23 Hs.591015 12

transcription factor activity

transcription factor activity

RNA polymerase II transcription factor activity

transcription cofactor activity

nucleus

transcription

regulation of transcription, DNA-dependent

regulation of transcription from RNA polymerase II promoter

signal transduction

sequence-specific DNA binding

 
210105_s_at FYN FYN oncogene related to SRC, FGR, YES   6 -112089179, -112089186 M14333 6q21 Hs.390567 244

nucleotide binding

protein-tyrosine kinase activity

protein-tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

protein binding

ATP binding

ATP binding

protein amino acid phosphorylation

protein amino acid phosphorylation

protein amino acid phosphorylation

calcium ion transport

intracellular signaling cascade

protein kinase cascade

learning

feeding behavior

cellular component unknown

transferase activity

identical protein binding

T cell receptor signaling pathway

Axon guidance

Focal adhesion

Adherens junction

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Fc epsilon RI signaling pathway

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

213134_x_at BTG3 BTG family, member 3   21 -17887842 AI765445 21q21.1-q21.2 Hs.473420 11

regulation of progression through cell cycle

cytoplasm

negative regulation of cell proliferation

negative regulation of progression through mitotic cell cycle

 
208869_s_at GABARAPL1 GABA(A) receptor-associated protein like 1   12 10256755 AF087847 12p13.2 Hs.524250 14

protein binding

protein binding

autophagic vacuole

microtubule

plasma membrane

protein targeting

synaptic transmission

beta-tubulin binding

GABA receptor binding

Regulation of autophagy

209373_at MALL mal, T-cell differentiation protein-like   2 -110198743 BC003179 2q13 Hs.185055 12

Golgi membrane

protein binding

plasma membrane

integral to membrane

cytoplasmic membrane-bound vesicle

clathrin-coated vesicle

cholesterol homeostasis

lipid raft

 
219718_at FLJ10986     1 59535327 NM_018291 1p32.1 Hs.444301 2

carbohydrate metabolism

 
206023_at NMU neuromedin U   4 -56156161 NM_006681 4q12 Hs.418367 16

receptor binding

regulation of smooth muscle contraction

regulation of smooth muscle contraction

signal transduction

neuropeptide signaling pathway

digestion

Neuroactive ligand-receptor interaction

203913_s_at HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)   4 -175647955 AL574184 4q34-q35 Hs.77348 25

biological process unknown

prostaglandin E receptor activity

cytosol

lipid metabolism

fatty acid metabolism

prostaglandin metabolism

transforming growth factor beta receptor signaling pathway

pregnancy

parturition

metabolism

cellular component unknown

15-hydroxyprostaglandin dehydrogenase (NAD+) activity

15-hydroxyprostaglandin dehydrogenase (NAD+) activity

oxidoreductase activity

lipoxygenase pathway

protein homodimerization activity

negative regulation of progression through cell cycle

NAD binding

 
202498_s_at SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14   12 -7857664 BE550486 12p13.31 Hs.419240 2

transporter activity

sugar porter activity

glucose transporter activity

spermatogenesis

carbohydrate transport

membrane

integral to membrane

cell differentiation

 
203180_at ALDH1A3 aldehyde dehydrogenase 1 family, member A3   15 99237583 NM_000693 15q26.3 Hs.459538 5

3-chloroallyl aldehyde dehydrogenase activity

aldehyde dehydrogenase [NAD(P)+] activity

alcohol metabolism

lipid metabolism

metabolism

oxidoreductase activity

Glycolysis / Gluconeogenesis

Ascorbate and aldarate metabolism

Fatty acid metabolism

Bile acid biosynthesis

Valine, leucine and isoleucine degradation

Lysine degradation

Arginine and proline metabolism

Histidine metabolism

Tyrosine metabolism

Phenylalanine metabolism

Tryptophan metabolism

beta-Alanine metabolism

Glycerolipid metabolism

Pyruvate metabolism

Propanoate metabolism

Butanoate metabolism

Limonene and pinene degradation

Metabolism of xenobiotics by cytochrome P450

209309_at AZGP1 alpha-2-glycoprotein 1, zinc   7 -99402287 D90427 7q22.1 Hs.546239 26

ribonuclease activity

fatty acid binding

extracellular region

cell adhesion

negative regulation of cell proliferation

protein carrier activity

lipid catabolism

antigen presentation

MHC class I receptor activity

MHC class I protein complex

 
204517_at PPIC peptidylprolyl isomerase C (cyclophilin C)   5 -122386978 BE962749 5q23.2 Hs.110364 12

peptidyl-prolyl cis-trans isomerase activity

cytoplasm

protein folding

signal transduction

cyclosporin A binding

isomerase activity

unfolded protein binding

 
205366_s_at HOXB6 homeobox B6   17 -44028097 NM_018952 17q21.3 Hs.98428 31

transcription factor activity

nucleus

regulation of transcription, DNA-dependent

development

determination of anterior/posterior axis, embryo

sequence-specific DNA binding

 
211184_s_at USH1C Usher syndrome 1C (autosomal recessive, severe)   11 -17472035 AB006955 11p15.1-p14 Hs.502072 22

protein binding

intracellular signaling cascade

visual perception

sensory perception of sound

cellular component unknown

response to stimulus

 
201289_at CYR61 cysteine-rich, angiogenic inducer, 61   1 85819047 NM_001554 1p31-p22 Hs.8867 47

regulation of cell growth

insulin-like growth factor binding

extracellular region

chemotaxis

cell adhesion

heparin binding

cell proliferation

morphogenesis

 
205548_s_at BTG3 BTG family, member 3   21 -17887842 NM_006806 21q21.1-q21.2 Hs.473420 11

regulation of progression through cell cycle

cytoplasm

negative regulation of cell proliferation

negative regulation of progression through mitotic cell cycle

 
203510_at MET met proto-oncogene (hepatocyte growth factor receptor)   7 116099694 BG170541 7q31 Hs.132966 131

nucleotide binding

protein-tyrosine kinase activity

receptor activity

hepatocyte growth factor receptor activity

protein binding

ATP binding

integral to plasma membrane

protein amino acid phosphorylation

signal transduction

development

cell proliferation

basal plasma membrane

membrane

transferase activity

Cytokine-cytokine receptor interaction

Axon guidance

Focal adhesion

Adherens junction

Epithelial cell signaling in Helicobacter pylori infection

Colorectal cancer

204352_at TRAF5 TNF receptor-associated factor 5   1 209566801, 209566579, 209586328 NM_004619 1q32 Hs.523930 41

signal transducer activity

protein binding

signal transduction

zinc ion binding

regulation of apoptosis

positive regulation of I-kappaB kinase/NF-kappaB cascade

metal ion binding

 
208868_s_at GABARAPL1 GABA(A) receptor-associated protein like 1   12 10256755 BF125756 12p13.2 Hs.524250 14

protein binding

protein binding

autophagic vacuole

microtubule

plasma membrane

protein targeting

synaptic transmission

beta-tubulin binding

GABA receptor binding

Regulation of autophagy

220161_s_at EPB41L4B erythrocyte membrane protein band 4.1 like 4B   9 -111041834, -110974075 NM_019114 9q31-q32 Hs.591901 3

structural constituent of cytoskeleton

binding

cytoplasm

cytoskeleton

cytoskeleton

cytoskeletal protein binding

membrane

 
212838_at DNMBP dynamin binding protein   10 -101626898 AB023227 10q24.2 Hs.500771 7

Rho guanyl-nucleotide exchange factor activity

protein binding

intracellular

cytoplasm

cytoskeleton

intracellular signaling cascade

regulation of Rho protein signal transduction

 
212143_s_at IGFBP3 insulin-like growth factor binding protein 3   7 -45918374 BF340228 7p13-p12 Hs.450230 170

regulation of cell growth

insulin-like growth factor binding

insulin-like growth factor binding

extracellular region

extracellular region

protein tyrosine phosphatase activator activity

negative regulation of signal transduction

positive regulation of apoptosis

positive regulation of myoblast differentiation

metal ion binding

 
218597_s_at ZCD1 zinc finger, CDGSH-type domain 1   10 59698920 NM_018464 10q21.1 Hs.370102 1

mitochondrion

zinc ion binding

metal ion binding

 
214175_x_at PDLIM4 PDZ and LIM domain 4   5 131621285 AI254547 5q31.1 Hs.424312 13

protein binding

zinc ion binding

metal ion binding

 
213113_s_at SLC43A3 solute carrier family 43, member 3   11 -56931004 AI630178 11q11 Hs.99962 4    
204491_at PDE4D phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)   5 -58302467 R40917 5q12 Hs.591763 44

3',5'-cyclic-nucleotide phosphodiesterase activity

3',5'-cyclic-AMP phosphodiesterase activity

soluble fraction

insoluble fraction

signal transduction

cellular component unknown

hydrolase activity

metal ion binding

Purine metabolism

204073_s_at C11orf9 chromosome 11 open reading frame 9   11 61279436 NM_013279 11q12-q13.1 Hs.473109 4    
217853_at TNS3 tensin 3   7 -47281277 NM_022748 7p12.3 Hs.520814 6

phosphoprotein phosphatase activity

protein amino acid dephosphorylation

intracellular signaling cascade

 
200851_s_at KIAA0174 KIAA0174   16 70486946 NM_014761 16q22.3 Hs.232194 10

protein binding

molecular function unknown

ER-Golgi intermediate compartment

 
202833_s_at SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1   14 -93914450 NM_000295 14q32.1 Hs.525557 119

serine-type endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

protein binding

extracellular region

extracellular space

acute-phase response

Complement and coagulation cascades

204992_s_at PFN2 profilin 2   3 -151165380 NM_002628 3q25.1-q25.2 Hs.91747 22

actin binding

protein binding

phosphatidylinositol-4,5-bisphosphate binding

cytoskeleton organization and biogenesis

regulation of actin polymerization and/or depolymerization

actin cytoskeleton

actin cytoskeleton organization and biogenesis

Regulation of actin cytoskeleton

216033_s_at FYN FYN oncogene related to SRC, FGR, YES   6 -112089179, -112089186 S74774 6q21 Hs.390567 244

nucleotide binding

protein-tyrosine kinase activity

protein-tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

protein binding

ATP binding

ATP binding

protein amino acid phosphorylation

protein amino acid phosphorylation

protein amino acid phosphorylation

calcium ion transport

intracellular signaling cascade

protein kinase cascade

learning

feeding behavior

cellular component unknown

transferase activity

identical protein binding

T cell receptor signaling pathway

Axon guidance

Focal adhesion

Adherens junction

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Fc epsilon RI signaling pathway

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

201124_at ITGB5 integrin, beta 5   3 -125964485 AL048423 3q21.2 Hs.536663 42

receptor activity

protein binding

cell adhesion

cell-matrix adhesion

integrin-mediated signaling pathway

development

integrin complex

membrane

integral to membrane

Focal adhesion

ECM-receptor interaction

Regulation of actin cytoskeleton

205626_s_at CALB1 calbindin 1, 28kDa   8 -91140013 NM_004929 8q21.3-q22.1 Hs.65425 21

vitamin D binding

calcium ion binding

protein binding

 
219255_x_at IL17RB interleukin 17 receptor B   3 53855616, 53855611 NM_018725 3p21.1 Hs.558512 12

regulation of cell growth

receptor activity

interleukin receptor activity

integral to plasma membrane

defense response

membrane

Cytokine-cytokine receptor interaction

203136_at RABAC1 Rab acceptor 1 (prenylated)   19 -47152677 NM_006423 19q13.2 Hs.11417 14

membrane

integral to membrane

identical protein binding

 
207935_s_at KRT13 keratin 13   17 -36910759, -36910761 NM_002274 17q12-q21.2 Hs.2785 21

structural molecule activity

structural constituent of cytoskeleton

intermediate filament

epidermis development

Cell Communication

205229_s_at COCH coagulation factor C homolog, cochlin (Limulus polyphemus)   14 30413515 AA669336 14q12-q13 Hs.21016 14

sensory perception of sound

 
201340_s_at ENC1 ectodermal-neural cortex (with BTB-like domain)   5 -73958990 AF010314 5q12-q13.3 Hs.104925 14

actin binding

protein binding

nucleus

cytoskeleton

development

nervous system development

 
218435_at DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15   13 42495361 NM_013238 13q14.1 Hs.438830 4

heat shock protein binding

 
222001_x_at FAM91A2 family with sequence similarity 91, member A2   1   AI160126 1q21.1 Hs.567947 Hs.634910 3    
208712_at CCND1 cyclin D1   11 69165053 M73554 11q13 Hs.523852 261

regulation of progression through cell cycle

G1/S transition of mitotic cell cycle

protein binding

nucleus

cell cycle

cellular component unknown

cell division

Cell cycle

Wnt signaling pathway

Focal adhesion

Jak-STAT signaling pathway

Colorectal cancer

221011_s_at LBH     2 30307900 NM_030915 2p23.1 Hs.567598 8    
201649_at UBE2L6 ubiquitin-conjugating enzyme E2L 6   11 -57075704 NM_004223 11q12 Hs.425777 19

ubiquitin conjugating enzyme activity

ubiquitin-protein ligase activity

ubiquitin-protein ligase activity

protein binding

ubiquitin cycle

ligase activity

Parkinson's disease

218066_at SLC12A7 solute carrier family 12 (potassium/chloride transporters), member 7   5 -1103499 NM_006598 5p15 Hs.172613 7

transporter activity

integral to plasma membrane

ion transport

potassium ion transport

sodium ion transport

chloride transport

symporter activity

potassium:chloride symporter activity

membrane

potassium ion binding

 
202185_at PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3   7 -100635978 NM_001084 7q22 Hs.153357 14

iron ion binding

protein binding

endoplasmic reticulum

protein modification

procollagen-lysine 5-dioxygenase activity

membrane

oxidoreductase activity

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

protein metabolism

L-ascorbic acid binding

metal ion binding

Lysine degradation

209201_x_at CXCR4 chemokine (C-X-C motif) receptor 4   2 -136588389 L01639 2q21 Hs.421986 213

rhodopsin-like receptor activity

receptor activity

signal transduction

G-protein coupled receptor protein signaling pathway

membrane

integral to membrane

C-C chemokine receptor activity

C-X-C chemokine receptor activity

Cytokine-cytokine receptor interaction

Axon guidance

Leukocyte transendothelial migration

211003_x_at TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)   20 -36190278, -36199766 BC003551 20q12 Hs.517033 87

protein-glutamine gamma-glutamyltransferase activity

protein-glutamine gamma-glutamyltransferase activity

calcium ion binding

GTP binding

extracellular matrix (sensu Metazoa)

cytosol

G-protein coupled receptor protein signaling pathway

acyltransferase activity

membrane

transferase activity

peptide cross-linking

peptide cross-linking

positive regulation of cell adhesion

Huntington's disease

214022_s_at IFITM1 interferon induced transmembrane protein 1 (9-27)   11 303852 AA749101 11p15.5 Hs.458414 12

regulation of progression through cell cycle

receptor signaling protein activity

protein binding

plasma membrane

immune response

cell surface receptor linked signal transduction

negative regulation of cell proliferation

response to biotic stimulus

integral to membrane

B cell receptor signaling pathway

218963_s_at KRT23 keratin 23 (histone deacetylase inducible)   17 -36332477 NM_015515 17q21.2 Hs.9029 6

structural molecule activity

intermediate filament

 
213329_at SRGAP2 SLIT-ROBO Rho GTPase activating protein 2   1 204582822 AA742261 1q32.1 Hs.497575 10

GTPase activator activity

intracellular

signal transduction

metal ion transport

metal ion binding

Axon guidance

217028_at CXCR4 chemokine (C-X-C motif) receptor 4   2 -136588389 AJ224869 2q21 Hs.421986 213

rhodopsin-like receptor activity

receptor activity

signal transduction

G-protein coupled receptor protein signaling pathway

membrane

integral to membrane

C-C chemokine receptor activity

C-X-C chemokine receptor activity

Cytokine-cytokine receptor interaction

Axon guidance

Leukocyte transendothelial migration

203734_at FOXJ2 forkhead box J2   12 8076625 NM_018416 12p13.31 Hs.120844 4

transcription factor activity

nucleus

transcription

regulation of transcription, DNA-dependent

sequence-specific DNA binding

 
203387_s_at TBC1D4 TBC1 domain family, member 4   13 -74757253 NM_014832 13q22.2 Hs.210891 13

GTPase activator activity

 
219188_s_at LRP16     11 -63522606 NM_014067 11q11 Hs.502814 6    
200660_at S100A11 S100 calcium binding protein A11 (calgizzarin)   1 -150271607 NM_005620 1q21 Hs.417004 26

ruffle

calcium ion binding

nucleus

cytoplasm

cytoplasm

signal transduction

negative regulation of DNA replication

negative regulation of cell proliferation

protein homodimerization activity

S100 beta binding

S100 alpha binding

calcium-dependent protein binding

 
207173_x_at CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)   16 -63538185 D21254 16q22.1 Hs.116471 21

ossification

calcium ion binding

protein binding

cell adhesion

homophilic cell adhesion

homophilic cell adhesion

membrane

integral to membrane

integral to membrane

 
205258_at INHBB inhibin, beta B (activin AB beta polypeptide)   2 120819468 NM_002193 2cen-q13 Hs.1735 43

ovarian follicle development

cytokine activity

hormone activity

extracellular region

defense response

growth factor activity

response to external stimulus

cell differentiation

growth

protein homodimerization activity

host cell surface receptor binding

positive regulation of follicle-stimulating hormone secretion

negative regulation of follicle-stimulating hormone secretion

negative regulation of hepatocyte growth factor biosynthesis

Cytokine-cytokine receptor interaction

TGF-beta signaling pathway

202206_at ARL4C ADP-ribosylation factor-like 4C   2 -235066426 AW450363 2q37.1 Hs.111554 7

nucleotide binding

GTPase activity

GTP binding

intracellular

nucleus

rRNA processing

small GTPase mediated signal transduction

 
203474_at IQGAP2 IQ motif containing GTPase activating protein 2   5 75734904 NM_006633 5q13.3 Hs.291030 12

actin binding

GTPase inhibitor activity

Ras GTPase activator activity

calmodulin binding

intracellular

signal transduction

actin cytoskeleton

regulation of small GTPase mediated signal transduction

Regulation of actin cytoskeleton

211919_s_at CXCR4 chemokine (C-X-C motif) receptor 4   2 -136588389 AF348491 2q21 Hs.421986 213

rhodopsin-like receptor activity

receptor activity

signal transduction

G-protein coupled receptor protein signaling pathway

membrane

integral to membrane

C-C chemokine receptor activity

C-X-C chemokine receptor activity

Cytokine-cytokine receptor interaction

Axon guidance

Leukocyte transendothelial migration

202478_at TRIB2 tribbles homolog 2 (Drosophila)   2 12774658 NM_021643 2p25.1-p24.3 Hs.591598 7

nucleotide binding

protein kinase activity

protein kinase inhibitor activity

ATP binding

cytoplasm

protein amino acid phosphorylation

regulation of MAPK activity

 
205201_at GLI3 GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)   7 -41970202 NM_000168 7p13 Hs.545043 34

protein import into nucleus, translocation

transcription factor activity

protein binding

intracellular

nucleus

cytoplasm

transcription

regulation of transcription, DNA-dependent

transcription from RNA polymerase II promoter

signal transduction

zinc ion binding

morphogenesis

metal ion binding

Hedgehog signaling pathway

212014_x_at CD44 CD44 molecule (Indian blood group)   11 35116992 AI493245 11p13 Hs.502328 192

receptor activity

collagen binding

hyaluronic acid binding

hyaluronic acid binding

integral to plasma membrane

cell adhesion

cell-matrix adhesion

membrane

cell-cell adhesion

ECM-receptor interaction

Hematopoietic cell lineage

209792_s_at KLK10 kallikrein 10   19 -56209338 BC002710 19q13.3-q13.4 Hs.275464 18

serine-type endopeptidase activity

extracellular region

proteolysis

cell cycle

negative regulation of progression through cell cycle

 
214079_at DHRS2 dehydrogenase/reductase (SDR family) member 2   14 23175421 AK000345 14q11.2 Hs.272499 8

alcohol dehydrogenase activity

nucleus

electron transport

metabolism

C21-steroid hormone metabolism

oxidoreductase activity

negative regulation of progression through cell cycle

gamma-Hexachlorocyclohexane degradation

Bisphenol A degradation

1- and 2-Methylnaphthalene degradation

Benzoate degradation via CoA ligation

Ethylbenzene degradation

Limonene and pinene degradation

208651_x_at CD24 CD24 molecule   6 -19611913 M58664 6q21 Hs.375108 26

plasma membrane

humoral immune response

GPI anchor binding

Hematopoietic cell lineage

204141_at TUBB2A tubulin, beta 2A   6 -3098902 NM_001069 6p25 Hs.300701 68

nucleotide binding

GTPase activity

structural molecule activity

structural constituent of cytoskeleton

GTP binding

cytoplasm

cytoskeleton

microtubule

microtubule-based movement

protein complex

protein polymerization

Gap junction

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

202458_at PRSS23 protease, serine, 23   11 86189210 NM_007173 11q14.1 Hs.25338 9

serine-type endopeptidase activity

proteolysis

peptidase activity

 
204041_at MAOB monoamine oxidase B   X -43510801 NM_000898 Xp11.23 Hs.46732 44

mitochondrion

mitochondrial envelope

electron transport

amine oxidase activity

electron carrier activity

membrane

integral to membrane

oxidoreductase activity

Glycine, serine and threonine metabolism

Arginine and proline metabolism

Histidine metabolism

Tyrosine metabolism

Phenylalanine metabolism

Tryptophan metabolism

206560_s_at MIA melanoma inhibitory activity   19 45973217 NM_006533 19q13.32-q13.33 Hs.631539 20

extracellular space

growth factor activity

cell proliferation

 
218084_x_at FXYD5 FXYD domain containing ion transport regulator 5   19 40337466 NM_014164 19q12-q13.1 Hs.333418 14

actin binding

ion channel activity

ion transport

membrane

integral to membrane

microvillus biogenesis

cadherin binding

negative regulation of calcium-dependent cell-cell adhesion

 
201744_s_at LUM lumican   12 -90021363 NM_002345 12q21.3-q22 Hs.406475 25

extracellular matrix structural constituent

collagen binding

extracellular region

extracellular matrix (sensu Metazoa)

fibrillar collagen

visual perception

collagen fibril organization

 
212845_at SAMD4A sterile alpha motif domain containing 4A   14 54104386 AB028976 14q22.2 Hs.98259 4

translation repressor activity

positive regulation of translation

 
208792_s_at CLU clusterin   8 -27510368 M25915 8p21-p12 Hs.436657 84

extracellular space

lipid metabolism

apoptosis

complement activation, classical pathway

cell death

innate immune response

 
200965_s_at ABLIM1 actin binding LIM protein 1   10 -116180859 NM_006720 10q25 Hs.438236 Hs.538331 15

actin binding

actin binding

protein binding

cytoskeleton organization and biogenesis

visual perception

zinc ion binding

organ morphogenesis

actin cytoskeleton

metal ion binding

Axon guidance

204883_s_at HUS1 HUS1 checkpoint homolog (S. pombe)   7 -47970307 AI968626 7p13-p12 Hs.152983 27

DNA damage checkpoint

double-strand break repair via homologous recombination

protein serine/threonine kinase activity

protein binding

nucleus

DNA repair

negative regulation of DNA replication

embryonic development

G1/S transition checkpoint

 
200079_s_at KARS lysyl-tRNA synthetase   16 -74219131 AF285758 16q23-q24 Hs.3100 20

tRNA binding

nucleotide binding

nucleic acid binding

lysine-tRNA ligase activity

lysine-tRNA ligase activity

lysine-tRNA ligase activity

ATP binding

soluble fraction

cytoplasm

cytoplasm

mitochondrion

protein biosynthesis

lysyl-tRNA aminoacylation

lysyl-tRNA aminoacylation

tRNA processing

ligase activity

Lysine biosynthesis

Aminoacyl-tRNA biosynthesis

Amyotrophic lateral sclerosis (ALS)

209355_s_at PPAP2B phosphatidic acid phosphatase type 2B   1 -56733022 AB000889 1pter-p22.1 Hs.405156 Hs.638793 11

phosphoprotein phosphatase activity

lipid metabolism

phosphatidate phosphatase activity

germ cell migration

membrane

integral to membrane

hydrolase activity

Glycerolipid metabolism

Glycerophospholipid metabolism

Sphingolipid metabolism

202071_at SDC4 syndecan 4 (amphiglycan, ryudocan)   20 -43387344 NM_002999 20q12 Hs.632267 45

biological process unknown

molecular function unknown

integral to plasma membrane

cytoskeletal protein binding

membrane

ECM-receptor interaction

Cell adhesion molecules (CAMs)

203962_s_at NEBL nebulette   10 -21110095, -21114604 NM_006393 10p12 Hs.5025 12

actin binding

structural constituent of muscle

actin cytoskeleton

regulation of actin filament length

 
202397_at NUTF2 nuclear transport factor 2   16 66438319 NM_005796 16q22.1 Hs.643529 17

protein binding

intracellular

protein transport

 
212774_at ZNF238 zinc finger protein 238   1 242283204, 242281207 AJ223321 1q44-qter Hs.69997 12

negative regulation of transcription from RNA polymerase II promoter

nuclear chromosome

nucleic acid binding

transcription factor activity

specific RNA polymerase II transcription factor activity

protein binding

protein binding

intracellular

nucleus

transcription

regulation of transcription, DNA-dependent

transport

chromosome organization and biogenesis (sensu Eukaryota)

zinc ion binding

metal ion binding

 
209094_at DDAH1 dimethylarginine dimethylaminohydrolase 1   1 -85556756 AL078459 1p22 Hs.379858 13

arginine catabolism

nitric oxide mediated signal transduction

zinc ion binding

dimethylargininase activity

hydrolase activity

metal ion binding

 
213069_at HEG1 HEG homolog 1 (zebrafish)   3   AI148659 3q21.2 Hs.477420 4    
221489_s_at SPRY4 sprouty homolog 4 (Drosophila)   5 -141670191 W48843 5q31.3 Hs.323308 9

protein binding

development

regulation of signal transduction

membrane

Jak-STAT signaling pathway

202201_at BLVRB biliverdin reductase B (flavin reductase (NADPH))   19 -45645540 NM_000713 19q13.1-q13.2 Hs.515785 10

biliverdin reductase activity

oxidoreductase activity

flavin reductase activity

cellular metabolism

coenzyme binding

Porphyrin and chlorophyll metabolism

208596_s_at UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3   2 234302511 NM_019093 2q37 Hs.124112 20

endoplasmic reticulum

microsome

metabolism

glucuronosyltransferase activity

membrane

integral to membrane

Pentose and glucuronate interconversions

Androgen and estrogen metabolism

Starch and sucrose metabolism

Porphyrin and chlorophyll metabolism

Metabolism of xenobiotics by cytochrome P450

206027_at S100A3 S100 calcium binding protein A3   1 -151786432 NM_002960 1q21 Hs.557609 16

calcium ion binding

zinc ion binding

 
207540_s_at SYK spleen tyrosine kinase   9 92603890 NM_003177 9q22 Hs.371720 153

nucleotide binding

non-membrane spanning protein tyrosine kinase activity

integrin binding

protein binding

ATP binding

cytoplasm

protein complex assembly

protein amino acid phosphorylation

leukocyte adhesion

integrin-mediated signaling pathway

intracellular signaling cascade

cell proliferation

organ morphogenesis

transferase activity

neutrophil chemotaxis

T cell receptor complex

Natural killer cell mediated cytotoxicity

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

219682_s_at TBX3 T-box 3 (ulnar mammary syndrome)   12 -113592441 NM_016569 12q24.1 Hs.129895 18

skeletal development

transcription factor activity

RNA polymerase II transcription factor activity

nucleus

transcription

regulation of transcription from RNA polymerase II promoter

morphogenesis

 
212098_at LOC151162     2   AL134724 2q21.3 Hs.4988 4    
202831_at GPX2 glutathione peroxidase 2 (gastrointestinal)   14 -64475624 NM_002083 14q24.1 Hs.2704 18

glutathione peroxidase activity

cytoplasm

response to oxidative stress

selenium binding

electron carrier activity

Glutathione metabolism

Arachidonic acid metabolism

210692_s_at SLC43A3 solute carrier family 43, member 3   11 -56931004 BC003163 11q11 Hs.99962 4    
214617_at PRF1 perforin 1 (pore forming protein)   10 -72027110 AI445650 10q22 Hs.2200 44

calcium ion binding

cytosol

virus-infected cell apoptosis

transformed cell apoptosis

cellular defense response

pathogenesis

membrane

integral to membrane

cytolysis

hemolysis of host red blood cells

Natural killer cell mediated cytotoxicity

Type I diabetes mellitus

205129_at NPM3 nucleophosmin/nucleoplasmin, 3   10 -103531072 NM_006993 10q24.31 Hs.90691 6

nucleic acid binding

nucleus

protein folding

unfolded protein binding

 
212473_s_at MICAL2 microtubule associated monoxygenase, calponin and LIM domain containing 2   11 12088713 BE965029 11p15.3 Hs.501928 8

cytoskeleton

electron transport

metabolism

zinc ion binding

oxidoreductase activity

metal ion binding

 
204820_s_at BTN3A3 butyrophilin, subfamily 3, member A3   6 26548741 NM_006994 6p21.3 Hs.167741 7

membrane

integral to membrane

 
216236_s_at SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3   12 -7963093 AL110298 12p13.3 Hs.419240 17

transporter activity

sugar porter activity

glucose transporter activity

glucose transporter activity

membrane fraction

carbohydrate metabolism

carbohydrate transport

glucose transport

membrane

integral to membrane

 
202731_at PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)   10 112621585 NM_014456 10q24 Hs.232543 17

protein binding

protein binding

nucleus

nucleus

cytoplasm

cytosol

apoptosis

apoptosis

cell aging

negative regulation of transcription

negative regulation of transcription

negative regulation of JNK activity

negative regulation of progression through cell cycle

positive regulation of translation

 
204034_at ETHE1 ethylmalonic encephalopathy 1   19 -48702711 NM_014297 19q13.31 Hs.7486 7

nucleus

mitochondrion

zinc ion binding

hydrolase activity

metal ion binding

 
209153_s_at TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)   19 -1560294 M31523 19p13.3 Hs.371282 93

transcription factor activity

protein binding

nucleus

regulation of transcription, DNA-dependent

 
204890_s_at LCK lymphocyte-specific protein tyrosine kinase   1 32512298, 32489426 U07236 1p34.3 Hs.470627 232

regulation of progression through cell cycle

regulation of progression through cell cycle

nucleotide binding

pericentriolar material

pericentriolar material

glycoprotein binding

protein-tyrosine kinase activity

protein-tyrosine kinase activity

protein-tyrosine kinase activity

protein serine/threonine phosphatase activity

protein serine/threonine phosphatase activity

ATP binding

plasma membrane

plasma membrane

protein amino acid phosphorylation

protein amino acid phosphorylation

protein amino acid phosphorylation

zinc ion homeostasis

zinc ion homeostasis

induction of apoptosis

induction of apoptosis

caspase activation

caspase activation

intracellular signaling cascade

intracellular signaling cascade

intracellular signaling cascade

Ras protein signal transduction

Ras protein signal transduction

protein C-terminus binding

transferase activity

protein kinase binding

hemopoiesis

hemopoiesis

T cell differentiation

T cell differentiation

SH2 domain binding

SH2 domain binding

response to drug

response to drug

CD4 receptor binding

CD8 receptor binding

phosphoinositide 3-kinase binding

lipid raft

lipid raft

positive regulation of T cell receptor signaling pathway

positive regulation of T cell receptor signaling pathway

positive regulation of T cell activation

positive regulation of T cell activation

ATPase binding

release of sequestered calcium ion into cytosol

regulation of lymphocyte activation

regulation of lymphocyte activation

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

201487_at CTSC cathepsin C   11 -87666408, -87693629 NM_001814 11q14.1-q14.3 Hs.128065 30

cysteine-type endopeptidase activity

dipeptidyl-peptidase I activity

lysosome

proteolysis

immune response

chloride ion binding

 
210139_s_at PMP22 peripheral myelin protein 22   17 -15073821 L03203 17p12-p11.2 Hs.372031 66

membrane fraction

integral to plasma membrane

synaptic transmission

peripheral nervous system development

sensory perception of sound

mechanosensory behavior

negative regulation of cell proliferation

membrane

 
219161_s_at CKLF chemokine-like factor   16 65143966, 65143972 NM_016951 16q21 Hs.15159 8

extracellular region

extracellular space

chemotaxis

chemokine activity

cell proliferation

membrane

integral to membrane

neutrophil chemotaxis

secretory pathway

macrophage chemotaxis

lymphocyte chemotaxis

 
202576_s_at DDX19B DEAD (Asp-Glu-Ala-As) box polypeptide 19B   16 68890572 AL553254 16q22.1 Hs.221761 11

nucleotide binding

RNA binding

ATP binding

nucleus

nuclear pore

cytoplasm

mRNA export from nucleus

ATP-dependent helicase activity

hydrolase activity

 
204401_at KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4   19 -48962526 NM_002250 19q13.2 Hs.10082 25

ion channel activity

voltage-gated potassium channel activity

calmodulin binding

membrane fraction

ion transport

potassium ion transport

defense response

voltage-gated potassium channel complex

calcium-activated potassium channel activity

membrane

integral to membrane

 
204933_s_at TNFRSF11B tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)   8 -120004977 NM_002546 8q24 Hs.81791 98

skeletal development

receptor activity

cytokine activity

protein binding

extracellular region

apoptosis

signal transduction

Cytokine-cytokine receptor interaction

210201_x_at BIN1 bridging integrator 1   2 -127522078, -127522076 AF001383 2q14 Hs.193163 49

protein binding

nucleus

cytoplasm

cell cycle

cell proliferation

actin cytoskeleton

regulation of endocytosis

cell differentiation

negative regulation of progression through cell cycle

 
220484_at MCOLN3 mucolipin 3   1 -85256353 NM_018298 1p22.3 Hs.535239 4

ion channel activity

ion transport

membrane

integral to membrane

 
220994_s_at STXBP6 syntaxin binding protein 6 (amisyn)   14 -24351143 NM_014178 14q12 Hs.508958 4

integral to membrane

vesicle-mediated transport

 
203435_s_at MME membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)   3 156280152, 156280327, 156280748 NM_007287 3q25.1-q25.2 Hs.307734 75

neprilysin activity

plasma membrane

integral to plasma membrane

proteolysis

cell-cell signaling

metallopeptidase activity

zinc ion binding

metal ion binding

Hematopoietic cell lineage

Alzheimer's disease

212298_at NRP1 neuropilin 1   10 -33526557, -33526555, -33506434 BE620457 10p12 Hs.131704 48

angiogenesis

receptor activity

vascular endothelial growth factor receptor activity

membrane fraction

cell adhesion

signal transduction

cell-cell signaling

nervous system development

axon guidance

positive regulation of cell proliferation

organ morphogenesis

membrane

integral to membrane

cell differentiation

Axon guidance

201920_at SLC20A1 solute carrier family 20 (phosphate transporter), member 1   2 113119997 NM_005415 2q11-q14 Hs.187946 11

receptor activity

inorganic phosphate transporter activity

transport

phosphate transport

symporter activity

membrane

integral to membrane

positive regulation of I-kappaB kinase/NF-kappaB cascade

 
214023_x_at TUBB2B tubulin, beta 2B   6 -3169513 AL533838 6p25 Hs.300701 3  

Gap junction

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

216252_x_at FAS Fas (TNF receptor superfamily, member 6)   10 90740267 Z70519 10q24.1 Hs.244139 316

transmembrane receptor activity

protein binding

soluble fraction

cytosol

protein complex assembly

apoptosis

anti-apoptosis

induction of apoptosis

immune response

signal transduction

signal transduction

membrane

integral to membrane

identical protein binding

regulation of apoptosis

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Apoptosis

Natural killer cell mediated cytotoxicity

Type I diabetes mellitus

210018_x_at MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1   18 54489597 AB026118 18q21 Hs.180566 34

signal transducer activity

protein binding

intracellular

proteolysis

anti-apoptosis

defense response

activation of NF-kappaB-inducing kinase

peptidase activity

caspase activity

regulation of apoptosis

positive regulation of I-kappaB kinase/NF-kappaB cascade

T cell receptor signaling pathway

B cell receptor signaling pathway

222088_s_at SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14   12 -7857664 AA778684 12p13.31 Hs.419240 2

transporter activity

sugar porter activity

glucose transporter activity

spermatogenesis

carbohydrate transport

membrane

integral to membrane

cell differentiation

 
204780_s_at FAS Fas (TNF receptor superfamily, member 6)   10 90740267 AA164751 10q24.1 Hs.244139 316

transmembrane receptor activity

protein binding

soluble fraction

cytosol

protein complex assembly

apoptosis

anti-apoptosis

induction of apoptosis

immune response

signal transduction

signal transduction

membrane

integral to membrane

identical protein binding

regulation of apoptosis

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Apoptosis

Natural killer cell mediated cytotoxicity

Type I diabetes mellitus

201567_s_at GOLGA4 golgi autoantigen, golgin subfamily a, 4   3 37259741 NM_002078 3p22-p21.3 Hs.344151 20

membrane fraction

Golgi trans face

vesicle-mediated transport

 
207126_x_at UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1   2 234333657 NM_000463 2q37 Hs.124112 85

endoplasmic reticulum

microsome

bilirubin conjugation

digestion

metabolism

estrogen metabolism

glucuronosyltransferase activity

membrane

integral to membrane

Pentose and glucuronate interconversions

Androgen and estrogen metabolism

Starch and sucrose metabolism

Porphyrin and chlorophyll metabolism

Metabolism of xenobiotics by cytochrome P450

204781_s_at FAS Fas (TNF receptor superfamily, member 6)   10 90740267 NM_000043 10q24.1 Hs.244139 316

transmembrane receptor activity

protein binding

soluble fraction

cytosol

protein complex assembly

apoptosis

anti-apoptosis

induction of apoptosis

immune response

signal transduction

signal transduction

membrane

integral to membrane

identical protein binding

regulation of apoptosis

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Apoptosis

Natural killer cell mediated cytotoxicity

Type I diabetes mellitus

203509_at SORL1 sortilin-related receptor, L(DLR class) A repeats-containing   11 120828129 NM_003105 11q23.2-q24.2 Hs.368592 17

transmembrane receptor activity

lipid transporter activity

integral to plasma membrane

lipid metabolism

lipid transport

intracellular protein transport

receptor mediated endocytosis

steroid metabolism

cholesterol metabolism

protein transporter activity

membrane

 
202442_at AP3S1 adaptor-related protein complex 3, sigma 1 subunit   5 115205517 NM_001284 5q22 Hs.406191 13

transporter activity

intracellular protein transport

insulin receptor signaling pathway

membrane coat adaptor complex

transport vesicle

coated vesicle membrane

 
200951_s_at CCND2 cyclin D2   12 4253198 AW026491 12p13 Hs.376071 50

regulation of progression through cell cycle

protein binding

nucleus

cell cycle

cell division

Cell cycle

Wnt signaling pathway

Focal adhesion

Jak-STAT signaling pathway

Colorectal cancer

212942_s_at KIAA1199 KIAA1199   15 78858766 AB033025 15q24 Hs.459088 10

sensory perception of sound

 
202166_s_at PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2   3 -196722513 NM_006241 3q29 Hs.535731 18

type 1 serine/threonine specific protein phosphatase inhibitor activity

protein binding

carbohydrate metabolism

glycogen metabolism

generation of precursor metabolites and energy

regulation of signal transduction

 
212099_at RHOB ras homolog gene family, member B   2 20510315 AI263909 2p24 Hs.502876 40

nucleotide binding

angiogenesis

protein binding

GTP binding

intracellular

nucleus

plasma membrane

transformed cell apoptosis

cell cycle

cell adhesion

small GTPase mediated signal transduction

endosome to lysosome transport

endosome membrane

protein transport

cell differentiation

positive regulation of angiogenesis

negative regulation of progression through cell cycle

 
203740_at MPHOSPH6 M-phase phosphoprotein 6   16 -80739271 NM_005792 16q23.3 Hs.344400 12

regulation of progression through cell cycle

M phase of mitotic cell cycle

protein binding

nucleus

 
204152_s_at MFNG manic fringe homolog (Drosophila)   22 -36195048 AI738965 22q12 Hs.517603 16

extracellular space

pattern specification

membrane

integral to membrane

transferase activity, transferring glycosyl groups

Notch signaling pathway

209398_at HIST1H1C histone 1, H1c   6 -26163946 BC002649 6p21.3 Hs.7644 14

nucleosome

DNA binding

nucleus

chromosome

nucleosome assembly

chromosome organization and biogenesis (sensu Eukaryota)

 
201566_x_at ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein   2 8739563 D13891 2p25 Hs.180919 54

protein binding

nucleus

nucleus

development

negative regulation of transcription

transcriptional repressor activity

negative regulation of transcription factor activity

TGF-beta signaling pathway

209121_x_at NR2F2 nuclear receptor subfamily 2, group F, member 2   15 94674949 M64497 15q26 Hs.347991 20

transcription factor activity

ligand-regulated transcription factor activity

steroid hormone receptor activity

transcription corepressor activity

nucleus

transcription

regulation of transcription from RNA polymerase II promoter

lipid metabolism

signal transduction

zinc ion binding

sequence-specific DNA binding

metal ion binding

 
201900_s_at AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)   1 45789084 NM_006066 1p33-p32 Hs.474584 19

aldehyde reductase activity

protein binding

glucose metabolism

aldehyde metabolism

alcohol dehydrogenase (NADP+) activity

electron carrier activity

oxidoreductase activity

Glycolysis / Gluconeogenesis

Glycerolipid metabolism

Caprolactam degradation

204830_x_at PSG5 pregnancy specific beta-1-glycoprotein 5   19 -48363735 NM_002781 19q13.2 Hs.502092 14

extracellular space

pregnancy

 
36552_at DKFZP586P0123     11 -73423189 AL080220 11q13.4 Hs.557938 2    
218031_s_at           NM_018589          
211709_s_at CLEC11A C-type lectin domain family 11, member A   19 55918416 BC005810 19q13.3 Hs.512680 15

nucleic acid binding

sugar binding

extracellular region

growth factor activity

positive regulation of cell proliferation

 
203218_at MAPK9 mitogen-activated protein kinase 9   5 -179595389 W37431 5q35 Hs.484371 69

nucleotide binding

protein serine/threonine kinase activity

JUN kinase activity

MAP kinase activity

protein binding

ATP binding

protein amino acid phosphorylation

response to stress

JNK cascade

transferase activity

MAPK signaling pathway

Wnt signaling pathway

Focal adhesion

Toll-like receptor signaling pathway

Fc epsilon RI signaling pathway

Insulin signaling pathway

GnRH signaling pathway

Adipocytokine signaling pathway

Type II diabetes mellitus

Epithelial cell signaling in Helicobacter pylori infection

Colorectal cancer

215108_x_at TNRC9 trinucleotide repeat containing 9   16   U80736 16q12.1 Hs.460789 2

chromatin

DNA binding

nucleus

regulation of transcription, DNA-dependent

 
212041_at ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1   16 -66029417 AL566172 16q22 Hs.106876 19

ion transport

ATP synthesis coupled proton transport

proton transport

proton-transporting two-sector ATPase complex

hydrogen-translocating V-type ATPase complex

hydrolase activity

metal ion binding

hydrogen-transporting ATP synthase activity, rotational mechanism

hydrogen-transporting ATPase activity, rotational mechanism

Oxidative phosphorylation

ATP synthesis

Cholera - Infection

Epithelial cell signaling in Helicobacter pylori infection

202268_s_at APPBP1 amyloid beta precursor protein binding protein 1   16 -65394282 NM_003905 16q22 Hs.460978 18

catalytic activity

protein binding

insoluble fraction

cytoplasm

DNA replication

ubiquitin cycle

cell cycle

signal transduction

ligase activity

NEDD8 activating enzyme activity

S-M checkpoint

regulation of apoptosis

protein neddylation

protein heterodimerization activity

Alzheimer's disease

244 Genes